Solution Conditions Tune and Optimize Loading of Therapeutic Polyelectrolytes into Layer-by-Layer Functionalized Liposomes
نویسندگان
چکیده
منابع مشابه
Charge Inversion and Layer-by-Layer Assembly of Flexible Polyelectrolytes
We have applied a continuum self-consistent field (SCF) theory to flexible polyelectrolytes on flat surfaces which are either uncharged or carrying the opposite charge as the polyelectrolytes. We examined in detail the effects of various parameters on the polyelectrolyte adsorption and surface charge compensation by the adsorbed polyelectrolytes. The ground-state dominance approximation (GSDA) ...
متن کاملLayer-by-layer assembly of imogolite nanotubes and polyelectrolytes into core-shell particles and their conversion to hierarchically porous spheres.
Core-shell particles were prepared by the layer-by-layer (LbL) assembly of imogolite (IMO) nanotubes and poly(sodium 4-styrenesulfonate) (PSS) on polystyrene particles (diameter: 800 nm) coated preliminarily with poly(diallyldimethylammonium chloride) (PDDA). PSS and imogolite were alternately adsorbed on the particles to form core-shell particles with one to three bilayers of PSS/IMO. Macropor...
متن کاملIn situ adhesion measurements utilizing layer-by-layer functionalized surfaces.
The adhesion between poly(dimethylsiloxane) (PDMS) hemispheres coated with layer-by-layer (LbL) assemblies of polyelectrolytes and rigid, planar substrates was investigated using Johnson, Kendall, and Roberts (JKR) contact mechanics. Measurements were performed against amine-functionalized glass slides both in air and in aqueous solutions of controlled pH. Despite the increased density of negat...
متن کاملPhenylboronic Acid-Functionalized Layer-by-Layer Assemblies for Biomedical Applications
Recent progress in the development of phenylboronic acid (PBA)-functionalized layer-by-layer (LbL) assemblies and their biomedical applications was reviewed. Stimuli-sensitive LbL films and microcapsules that exhibit permeability changes or decompose in response to sugars and hydrogen peroxide (H2O2) have been developed using PBA-bearing polymers. The responses of PBA-modified LbL assemblies ar...
متن کاملSecond Harmonic Generation Diagnostic of Layer by Layer Deposition from Disperse Red 1–Functionalized Maleic Anhydride Copolymer
Layer-by-layer (LBL) electrostatic assembly of poly-electrolytes is proving to be an increasingly rich and versatile technique for the formation of multilayered thin films with a wide range of electrical, magnetic, and optical properties. In the present work we synthesized a new nonlinear optical (NLO) maleic acid copolymer containing Disperse Red 1 moieties, built-up multilayer assemblies by a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Nano
سال: 2019
ISSN: 1936-0851,1936-086X
DOI: 10.1021/acsnano.9b00792